phenobarbital sodium contraindications for Dummies
phenobarbital sodium contraindications for Dummies
Blog Article
benzhydrocodone/acetaminophen and pentobarbital equally increase sedation. Stay away from or Use Alternate Drug. Limit use to clients for whom alternative remedy possibilities are insufficient
DESCRIPTION The barbiturates are nonselective central nervous process depressants that happen to be generally used as sedative hypnotics and likewise anticonvulsants in subhypnotic doses. The barbiturates and their sodium salts are matter to manage under the Federal Controlled Substances Act (See “Drug Abuse and Dependence” area). The sodium salts of amobarbital, pentobarbital, phenobarbital, and secobarbital are offered as sterile parenteral solutions. Barbiturates are substituted pyrimidine derivatives by which the basic structure frequent to these drugs is barbituric acid, a substance that has no central anxious system (CNS) activity.
pentobarbital will lower the extent or effect of docetaxel by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Not known.
Contraindicated (1)pentobarbital will decrease the extent or effect of roflumilast by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will decrease the extent or effect of fosamprenavir by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
pentobarbital will lessen the extent or effect of ethinylestradiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Keep away from or Use Alternate Drug. The efficacy website of hormonal contraceptives can be decreased. Usage of a nonhormonal contraceptive is recommended.
pentobarbital will reduce the level or effect of quetiapine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.
pentobarbital will reduce the level or effect of elagolix by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
pentobarbital will decrease the level or effect of disopyramide by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Mysterious.
pentobarbital will decrease the level or effect of solifenacin by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
pentobarbital will lessen the level or effect of losartan by affecting hepatic enzyme CYP2C9/10 metabolism. Slight/Significance Unfamiliar.
pentobarbital will decrease the extent or effect of zonisamide by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Not known.
pentobarbital will reduce the level or effect of tofacitinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch. Lack of, or lessened reaction to tofacitinib may take place when coadministered with powerful CYP3A4 inducers
pentobarbital will lessen the extent or effect of capivasertib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Keep away from or Use Alternate Drug. Sturdy or moderate CYP3A inducers minimize capivasertib exposure, which may lower efficacy.